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GLP-1 medications can cause fatigue through several mechanisms including reduced caloric intake due to appetite suppression, gastrointestinal side effects leading to dehydration and electrolyte imbalances, and metabolic adjustment to improved blood glucose control

Low dose, slow increase

Understanding the broader GLP-1 and fatigue connection helps contextualize why tiredness during treatment can feel so pervasive

Typical monitoring intervals include: No diabetic retinopathy at baseline: recheck at six to 12 months Mild diabetic retinopathy: every six months, or at three months if A1C drops rapidly Moderate to severe diabetic retinopathy or macular edema: every three months with retina specialist coordination Proliferative retinopathy or treated macular edema: follow the retina specialist schedule Advanced imaging helps us detect subtle retinal changes before they affect your vision