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Comparing thyroid risk across GLP-1 receptor agonists Tirzepatide is not the only medication carrying a thyroid C-cell tumor boxed warning

Brown, for example, says she hasnt noticed an increase in GI problems when patients take both medicines, but it is theoretically possible. Side effects often improve over time as your body adjusts, but combining the two could make it harder to tolerate one or both

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When you eat, your gut releases glucagon-like peptide-1, which signals your pancreas to release insulin, tells your brain you are full, and slows gastric emptying so nutrients absorb more gradually

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