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Clinically, treatment drugs for chronic pain are mainly non-steroidal anti-inflammatory analgesics, opioid analgesics, and auxiliary drugs: such as antidepressants and anxiety drugs (94)

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Across all semaglutide treatment arms, the most frequent AEs were gastrointestinal disorders (most commonly nausea, diarrhoea and vomiting), the majority of which were mild/moderate in severity

The time varies per individual, but most people begin to notice effects within a few weeks