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YangXHeiCLiuPSongYThomasTTshimangaSet alInhibition of mTOR pathway by rapamycin reduces brain damage in rats subjected to transient forebrain ischemia

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Tirzepatide is a first-in-class and only GLP-1/GIP dual agonist

Peptides are found naturally in tissues, blood, and secretions, but can be manufactured for research and medical purposes

Mechanism of Action: Morphine acts on (mu) opioid receptors in the CNS and produces analgesia by: Activating G-protein coupled receptors Opening K channels hyperpolarization of neurons Closing Ca channels reduced neurotransmitter release Decreasing release of pain mediators like substance P and glutamate Results in Pain signal transmission in brain and spinal cord strong analgesia