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9 Globally, the market for GLP-1s reached $50 billion in 2024, with projections to more than double by 2030 10 and already millions of Americans are prescribed the treatment

Yet the chemical space explored by these peptides is a fraction of that embodied by natural products and pharmaceuticals, and most peptide leads require exhaustive medicinal chemistry optimization to improve potency and physicochemistry

it plays a role in mood regulation, appetite, and quality of life