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Semax was studied in 30 patients, whose outcomes were compared with a control group of 80 patientsmatched for stroke severity and lesion locationwho received conventional therapy

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Its modulation of cortisolthe bodys primary stress hormonemay contribute to more stable sleep cycles and a reduction in sleep disturbances

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While cortisol concentrations did not differ between male and female bonobos 86,87 , cortisol levels gradually increased during the ontogeny of wild bonobos 87