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It is important to distinguish between dark urine caused by concentration (which appears deep yellow to amber and clears with increased fluid intake) and abnormal pigmentation suggesting pathology (such as tea-coloured urine indicating bilirubin, or red-brown urine suggesting blood or myoglobin)

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2 Conclusions GLP-1 RAs are multisystemic interventions capable of simultaneously addressing both physiological and some psychological barriers to weight loss