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And just before we move on to clinically assessing things outside of blood histamine, I did want to just ask you to share the why histamine intolerance is often more challenging or more prevalent in women, and youve kind of hinted at the estrogen connection there, but can you just give us a little bit more detail around that

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But you do need to spend something: either money or an enormous amount of your own time

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Intracellular signaling mechanisms of the melanocortin receptors