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We chose 4 h of hypoxia for subsequent experimental detection (Supplemental Fig

Furthermore, GSH supplementation has been shown to protect HIV patients from a variety of opportunistic diseases by (i) mitigating oxidative stress and chronic inflammation in HIV-associated neurodegenerative diseases, (ii) improving Th17 responses in HIV patients who have impaired gut mucosal defenses, and (iii) restoring Th1 responses to protect patients from TB coinfection

4.4 Gaps and future directions 4.4.1 Need for better in vivo and clinically relevant models Translational research is lacking in confirming the in vitro biofilm data (obtained using microtiter plates and flow devices) in the context of a human infection

Konturek et al

Injections are accomplished with standard gauge needles used for administering liquid formulation or compositions