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The final concentration of FOXO4-DRI and ABT-263 was 25 and 1.25 M in 2% FBS basal medium

Acknowledgements We acknowledge support from the National Institute on Alcohol Abuse and Alcoholism (AA029831), National Institute on Aging (AG057557, AG061388, AG062272, AG07664), from National Cancer Institute Case Comprehensive Cancer Center (CA221718, CA043703, CA2332216) Ethics declarations Competing interests The authors declare no competing interests

In addition, women have lower levels of alcohol dehydrogenase, the alcohol-metabolizing enzyme

It also highlighted significant weight loss benefits, which are particularly valuable for overweight or obese patients with CKD