BPC 157 alone To make needed distinction between the effect of BPC 157 itself and the effect of BPC 157 with administration of NSAIDs, BPC 157 was given as intraperitoneal and intragastric administration, or prolonged administration in drinking water in healthy rats to adequately correspond to different application protocols of NSAIDs, intraperitoneal (aspirin, diclofenac, paracetamol, celecoxib), intragastric (aspirin) application or prolonged applications (ibuprofen)
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For example, sugar alcohols like sorbitol or mannitol (used in some chewable or effervescent preparations) can have osmotic effects, drawing water into the intestinal lumen and potentially leading to loose stools in sensitive individuals