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We evaluate at the end of each cycle before deciding whether to repeat, adjust the dose, add a stack partner like TB-500, or transition to a maintenance approach

After blocking, the membranes were incubated with mouse anti-GST (Santa Cruz Biotechnology), TG2 7 , and FLAG antibodies (Sigma-Aldrich) at 4 C overnight

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The approval is the second for Krazati, which is also FDA-authorized to treat KRASG12C-mutated locally advanced or metastatic non-small cell lung cancer