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Profibrotic epithelial TGF-1 signaling involves NOX4-mitochondria cross talk and redox-mediated activation of the tyrosine kinase FYN

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Conclusion Altogether, preclinical and clinical studies on the role of TNF in AD pathogenesis revealed that TNF affects multiple functions, including neuronal activity, neurotransmission, sleep regulation, and astrocyte-mediated glutamate release

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