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In this Review, we posit that eight molecular hallmarks are common denominators in cardiovascular ageing, namely disabled macroautophagy, loss of proteostasis, genomic instability (in particular, clonal haematopoiesis of indeterminate potential), epigenetic alterations, mitochondrial dysfunction, cell senescence, dysregulated neurohormonal signalling and inflammation

This assay is optimized for enzymatic antioxidants and measures the competition kinetics of O reduction between cytochrome C (a probe) and the test sample (Xie et al., 2016a, b)

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