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El ensayo STEP 1 demostr una prdida de peso promedio de 14.9% del peso corporal inicial a las 68 semanas, comparado con 2.4% en el grupo placebo

This study also found the skin gained protection against UV damage even though the conversion was slow and small

Tirzepatide is the first combination of entero-pancreatic hormones [dual GLP-1 and glucose-dependent insulinotropic polypeptide (GIP) RA] that has been approved for T2D management based on the findings from the phase 3 SURPASS programme

Most side effects are mild and improve with time and careful dosing

The neurochemical adaptation period varies significantly between individuals