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Cancer Early interest in coenzyme Q 10 as a potential therapeutic agent in cancer was stimulated by an observational study that found that individuals with lung, pancreas, and especially breast cancer were more likely to have low plasma coenzyme Q 10 concentrations than healthy controls (83)
Katoch et al
This dual approach revealed patterns I hadnt anticipated
289 Linking ERAD to calcium homeostasis High ER Ca 2+ levels are required for proper ER function, and disruption of Ca 2+ homeostasis promotes the deposition of misfolded proteins within the ER
Antibodies used for immunoblotting include p16 (sc-468, Santa Cruz), Nrf2 (sc-722, Santa Cruz), Elastin (Ab21607, Abcam), -actin (A3854, Sigma-Aldrich)
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