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L-lysine and L-proline amino acids are the precursors of hydroxylysin
Under oxidative stress and induced by excessive ROS generation, Nrf2 is released from its inhibitor Keap1, allowing its translocation into the nucleus (Kasprzak et al., 2020), where it binds to the antioxidant response element (ARE) present in the DNA sequence of numerous antioxidant enzymes like glutathione-S-transferase, -glutamyl cysteine synthetase (glutamate cysteine ligase), heme oxygenase 1, and paraoxonase-1 inducing their transcription, managing the phase II response to oxidative stress (Kasprzak et al., 2020)
Theo di nh hng ca glucosamine Nu bn ang i mt vi cc vn sc khe nh hen suyn, huyt p cao, hoc ri lon ng mu, vic theo di st sao tnh trng sc ca bn thn khi ung glucosamine
[DOI] [PubMed] [Google Scholar] 40.Paternoster R, Brame R, Mazerolle P, Piquero A
Obesity and cancer risk: Emerging biological mechanisms and perspectives[J]
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