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1) GLP-1: appetite control + slower digestion GLP-1 activation (the pathway used by semaglutide/Wegovy) helps people feel fuller sooner, reduces appetite, and slows gastric emptying often reducing snacking and lowering overall intake

The normalization pattern suggests feedback regulation, where restored enzyme levels trigger homeostatic mechanisms that prevent overshoot

The expression of relative mRNA was normalized to that of the housekeeping gene 18S.Primer sequences used are provided in Supplementary Table 2

While a balanced diet and exercise is the foundation sometimes supplemental nutrition can be beneficial

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