Needless to say, this is a topic the researchers tackled
Although genetic variations at these loci have long been considered neutral, the availability of a significant amount of epidemiological data and the use of mathematical models have allowed us to discover that some combinations of alleles at these loci may be subject to selection and that some combinations in some hypervirulent lines are associated with small gains in fitness for meningococcal transmission (Buckee et al., 2008)

In controlled research environments, Epithalon has been used to explore: Telomerase activation and telomere length dynamics in cell culture Oxidative stress and free-radicalrelated cellular damage Regulation of specific gene promoters related to immune function, extracellular matrix integrity, and circadian signaling Fibroblast activity, collagen and extracellular matrix maintenance in skin models Experimental tumor-growth kinetics and radiation-response pathways Melatonin synthesis and circadian-related protein expression Retinal structure and electrophysiologic function in selected ocular models All findings remain exploratory and model-dependent, and are interpreted strictly within the context of basic and translational research
The gut microbiota and diabetic nephropathy: an observational study review and bidirectional Mendelian randomization study
Curr Med Chem 20(28):34713487 Kayili HM, Salih B (2016) Fast and efficient proteolysis by reusable pepsin-encapsulated magnetic sol-gel material for mass spectrometry-based proteomics applications