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We then created a total score by summing the 5 scales and compared outcomes based on treatment group and gender with separate Mann Whitney rank sums test due to the skewed distributions, using SPSS version 27 (Armonk, NY: IBM Corp)

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Note that the solutions of the sensitivity differential equations are vectors of values over the time interval we consider (PN11 through PN28, expressed in minutes), so in calculating the normalized local sensitivity coefficients (shown in Fig

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