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Under physiological conditions, ROS are generated in the heart mainly from the mitochondrial electron transport chain, nitric oxide synthases (NOS), NADPH oxidases (NOX), and xanthine oxidase (XO) in small quantities [7, 8]

Indeed, the association of doxorubicin with bioenergetic toxicity is well stated in the literature 32,33,34

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These transcripts are tissue-specific, have different functional consequences but no recognizable polyadenylation signal in their 3UTRs, and they are tissue-specific

Structure-guided discovery of the novel covalent allosteric site and covalent inhibitors of fructose-1,6-bisphosphate aldolase to overcome the azole resistance of candidiasis