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Significant concerns In January, the National Association of Medicaid Directors told the federal Centers for Medicare & Medicaid Services that state Medicaid departments had significant concerns over the fiscal impacts of the Biden proposal to require coverage of GLP-1s, and strongly recommend that CMS maintain the current state option to cover or not cover anti-obesity medications. But others say covering the drugs will yield long-term savings

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People with treatment-resistant hypertension, especially those with co-existing diabetes, obesity, heart failure (HF), or chronic kidney disease (CKD) may particularly benefit from SGLT2-i and GLP-1RA

Meanwhile, a study that used data from over 520,000 patients suggests that those who started taking a GLP-1 (such as Zepbound) to manage their Type 2 diabetes had a higher rate of developing NAION within one year than the control group

The organizational chart below summarizes the selection of articles for the present study