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It's important to understand that these medications follow a gradual dose escalation schedule to minimize side effects, particularly nausea and gastrointestinal discomfort

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2014 Feb;28(2):514-9

4h) compared to Gclc fl/fl FoB and MZB

Primary iron overload is caused by genetic disorders that dysregulate the absorption of dietary iron, whereas secondary iron overload develops due to repeated blood transfusions, drug-induced toxicity, or excess consumption of iron [64]