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However, these methods have also a disadvantage associated with a difficulty of application thereof to industrial-scale production due to a low concentration of reactants and a prolonged reaction time of 2 to 3 days

Mol Psychiatry 28:284297 Frost G, Sleeth ML, Sahuri-Arisoylu M, Lizarbe B, Cerdan S, Brody L, Anastasovska J, Ghourab S, Hankir M, Zhang S, Carling D, Swann JR, Gibson G, Viardot A, Morrison D, Louise Thomas E, Bell JD (2014) The short-chain fatty acid acetate reduces appetite via a central homeostatic mechanism

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