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[27] [7] Patients should report any suspected side effects via the MHRA Yellow Card scheme (yellowcard.mhra.gov.uk)

When used with exfoliants or retinoids, they produce micro-tears and irritation

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88 In terms of immune regulation, it has been documented that interleukin-4 (IL-4) and IL-13 inhibit the expression of GPX4 in some tissues (including heart, spleen, lung, and kidney), while the expression of ALOX15 increases, resulting in the massive production of arachidonic acid metabolites and inducing lipid peroxidation