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Interestingly, Pseudomonas nitroreducens GGT (PnGGT) exhibits higher hydrolytic activity than transpeptidase activity despite high sequence similarity with EcGGT ( Picrophilus torridus GGT (PtGGT), the replacement of an aromatic residue tyrosine at position 327 by asparagine (corresponding residue in EcGGT) introduced significant transpeptidase activity in PtGGT, while the native enzyme exhibited only hydrolytic activity ( Importance of Lid Loop in Catalysis The presence of a unique lid-loop region in the small subunit of GGT of different bacterial and mammalian homologues as shown in multiple sequence alignment (Supplementary Figure 1) has structural and functional significance

More Info Physical Appearance Stability Solubility Amino Acid Sequence Background Fertirelin, a potent gonadotropin-releasing hormone (GnRH) analogue, is crucial for fertility regulation in animals

Une biodisponibilit pas si limite

It is artificially created by treating graphite with strong oxidisers such as sulphuric acid

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