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involving over 18,000 patients found that while general complications were rare and comparable between patients undergoing surgery for autoimmune thyroid disease and those with multinodular goitre, the risk of transient (15.3%) and permanent (1.1%) hypoparathyroidism was significantly higher in HT patients than in those undergoing surgery for multinodular goitre (12.9% and 0.9%, respectively) (57)

doi: 10.1210/jcem.81.11.8923843 7 PataniABalramDYadavVKLianKYPatelASahooDK

Clinical data beyond 26 weeks is limited, but observational evidence suggests diminishing returns after week 20-24 as VAT reduction plateaus and the body reaches a new homeostatic setpoint