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Therefore, based on the current findings showing a downregulation in NTS PPG expression by HFSD diet induced obesity, it is tempting to speculate that this effect might exacerbate or perpetuate a chronic hyperphagic effect that sustains obesity

Compound 2 was added to the solution of ( N - tert -butoxycarbonyl)-L-selenocysteine methyl ester in either methanol or phosphate buffer and incubated for 40 min, 24 h, and 120 h under N 2 gas balloon

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Because of its anti-androgenic activity and the requirement of testosterone for male morphogenesis, spironolactone may have the potential for adversely affecting sex differentiation of the male during embryogenesis