is tirzepatide a glp1 FDA approval for Zepbound (tirzepatide) injection, the first and only obesity treatment of its kind that activates both GIP and GLP-1 hormone receptors - Eli Lilly Beyond glycemia: Comparing tirzepatide to

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Thus, a meta-analysis comprising individuals with chronic constipation revealed a positive effect of inulin consumption on bowel function, improving the stool frequency, stool consistency, transit time, and hardness of stool, while no efficacy was shown for pain and bloating [47]

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Emerging evidence also points to specific lncRNAs (e.g., LINC-PINT, NEAT1) that are differentially expressed in HT and may regulate immune-related gene networks (Abdalrahman et al., 2025)