What an Endocrinologist Actually Sees To a specialist, obesity isnt a cosmetic issue its a complex, chronic metabolic condition shaped by genetics, hormones, gut signaling, sleep, and stress, not simply a matter of willpower
-Ketoglutarate, an intermediate metabolite of the tricarboxylic acid cycle, has been shown to suppress NLRP3 inflammasome activation and improve ovarian reserve in POI rat models (Liu K
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However, when metabolic pathways are impaired, the accumulation of intermediate products may exert toxic effects
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