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In the Xenopus oocyte expression system, examination of rKOR regulation on the activation of potassium channels revealed that over-expression of GRK3 or 5 alone did not promote a significant desensitization which requires both GRK and arrestin 3 (Appleyard et al., 1999)

PMID 15113413

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Review confirming 30% collagen reduction in first five years, then 2% per year for 15 years

Why GLP-1 Therapy May Still Be Effective With Steroids Despite this metabolic conflict, GLP-1 medications can still support weight management in patients taking corticosteroidsbut the approach must be individualized