While the expiration date is not a strict cut-off after which a medication becomes toxic, using expired semaglutide could lead to reduced effectiveness
You can see why FDA reviewers, in Reuters account, raised impurity and toxicity concerns and pointed to thin human data (Reuters)
Are incompatible with GSH stability
Body weight Dose-dependent reductions in body weight were evident vs placebo with tirzepatide 5 mg (6.31 kg [95% CI 4.38, 8.25], I 2 70%), 10 mg (8.43 kg [95% CI 6.77, 10.09], I 2 68%) and 15 mg (9.36 kg [95% CI 6.20, 12.53], I 2 91%) (Fig
Also in the event that you have struggled with disordered eating in the past fasting might not be a good idea unless you are in sound mental health