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In the CNS, ammonia is theorized to cause inflammation, oxidative injury, astrocyte swelling, increased NMDA activity, and osmotic stress which can all lead to brain injury and cerebral edema

Vitamin B12 Deficiency and Mood Disorders: A deficiency in vitamin B12 can contribute to a variety of neurological and psychiatric symptoms, such as mood changes, irritability, and even depression

Rich in phenolic and flavonoid metabolites, Scrophularia radix inhibits -glucosidase and -amylase, activates the AMPK pathway, and regulates glucose metabolism while alleviating insulin resistance

Nasal congestion: Using a nasal spray can sometimes cause or worsen nasal congestion

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