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But the reviewers graded the evidence as very low quality, with high risk of bias, and the trials were concentrated in a handful of countries: three in China, one in Russia, one in Romania, one unclear

& Wakino, S

A few have early clinical data

A 2006 study by Kossoy et al

Studies of patients with Hashimotos thyroiditis and subclinical hypothyroidism showed that supplementation of Myo and selenomethionine significantly decreased TSH, TPOAb, and TGAb concentrations, while simultaneously increasing thyroid hormones levels and restoring euthyroid state in patients with autoimmune thyroiditis (203, 204)

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