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(For all of last year, Mounjaro generated $482.5 million in revenues.) Based in Berkeley, CA, Carmot focuses on developing drugs for metabolic diseases that include obesity and diabetes, as well as Prader-Willi syndrome, the disease targeted by Carmots sole disclosed preclinical candidate CT-PYY, a long-acting PYY analog delivered as an injectable peptide

Another drug of this class, dapagliflozin, is being examined in the DEAN trial, a phase 3 RCT addressing NASH in patients with DM2

2017 Aug;69(8):578-594

the dose itself adjusts based on clinical response

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