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Efforts should be made to control for confounding factors and to account for the complexity of dietary patterns and lifestyle habits

Since MTHFR controls the detoxification of homocysteine and the supply of methyl groups for SAM synthesis, a reduction in its activity can affect homocysteine metabolism and disturb cellular methylation processes

It helps enhance detoxification, improve antioxidant defence, and support overall vitality

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Although full safety and dosing studies will be required for any new molecule, the fact that 5-nitroimidazole ethers are derived from a clinically approved drug provides a strong foundation for preclinical development