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Frequency depends on the specific peptide

Conversely, histone acetylation by histone acetyltransferases (HATs) loosens chromatin, facilitating gene transcription [260]

Milicevic et al., 2022)

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Global awareness of this plant rose after 1967, when the International Association of Applied Microbiology described Spirulina as a food of the future. Soon thereafter, the United States Food and Drug Administration (FDA) classified Spirulina as generally regarded as safe (GRAS), which accelerated its commercial cultivation