Recent interest has emerged around GLP-1 receptor agonists like Ozempic for fibromyalgia management, driven by growing evidence that these medications activate anti-inflammatory pathways beyond glucose control
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Its not clear how the drugs might be tied to that decreased risk, however, and this might be one of those outcomes that needs further study
Reference Tolhurst et al., Diabetes (2012) Reference Shah & Vella, Reviews in Endocrine and Metabolic Disorders (2014) When SCFA-producing microbes decline, GLP-1 signaling weakens and metabolism slows
Some have raised concerns that Ozempic causes lean mass loss such as muscle and bone, things you want to keep