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Recent supply data shows steady double-digit growth for injectable preparation products

Excessive peritoneal iron accumulation leads to overproduction of reactive oxygen species (ROS)-a group of highly reactive chemicals formed from oxygen, which at high concentrations can damage DNA, RNA, proteins, and lipids within the cell (20)-and enhanced activation of nuclear factor kappa-B (NF-B), which, by promoting the expression of matrix metalloproteinases (MMPs), exacerbates inflammation, angiogenesis, and cell adhesion

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[DOI] [PMC free article] [PubMed] [Google Scholar] 19.Blidisel A., Marcovici I., Coricovac D., Hut F., Dehelean C.A., Cretu O.M

[17] [18] Moderate doses of gliotoxin have also been found to exhibit an anti-inflammatory effect in vivo due to the suppression of NF-B activity by gliotoxin