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Cohorts receiving either 1 mg or 3 mg completed their dosing regimens, but a severe allergic reaction occurred in one patient after a singular 6 mg dose of AZD2820 (63, 64)

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In DIO mice, GLP-1GIPLani decreased body weight, food intake and hyperglycaemia with improved efficacy compared with GLP-1GIP, semaglutide or Lani (Fig

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