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Hypothyroidism is diagnosed in patients with PWS with a prevalence ranging 472% [40, 41]

For context, many diabetes medications struggle to achieve a 1% reduction

UTIs, presumably due to reduced immune cell function

or a BMI of 27 or higher with prediabetes, a prior heart attack, a prior stroke, or peripheral artery disease

This means the agency does not review compounded drugs for safety, effectiveness or quality before they are marketed. The Obesity Action Coalition (OAC), The Obesity Society (TOS), and The Obesity Medicine Association (OMA) have released a statement expressing their concerns for patients using the compounded GLP-1 alternatives