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The most common side effects of selpercatinib included diarrhea, high blood pressure, and increased blood levels of two liver enzymesa sign of liver toxicity

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The recommendation is to take between 25100 micrograms per day, as this amount has been shown to maintain healthy levels of vitamin B12 levels in older people

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Contraindications GLP-1 medications are contraindicated in patients with a personal or family history of medullary thyroid carcinoma (MTC) or Multiple Endocrine Neoplasia syndrome type 2 (MEN2)