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On average, individuals using FDA-approved medications may lose 15-20% of their body weight over several months when combined with a healthy diet and regular exercise
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The combined inflammatory impact of cytotoxicity by CD8+ T cells, immune-mediated perturbations of the islet ECM, and other mechanistic changes lead to cell death and decreased cell mass in a time-dependent manner ( Figure 2 )
Same 2.5 mg target dose
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