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Over-the-counter antacids and proton pump inhibitors like omeprazole are compatible with GLP-1 therapy

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The notable movement of the extracellular end of TM7 may translate to the inward shift of its cytoplasmic end

Importantly, tirzepatide carries a boxed warning for risk of thyroid C-cell tumors, including medullary thyroid carcinoma (MTC), and is contraindicated in patients with a personal or family history of MTC or in patients with Multiple Endocrine Neoplasia syndrome type 2 (MEN2)

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