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Nrf2 activation suppresses ROS in antigen-presenting dendritic cells enhancing their capacity to interact with and promote the transformation of nave CD8 T cells into cytotoxic T lymphocytes enabling cytotoxic T-cells to eliminate virally infected cells (Kesarwani et al., 2013

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During winter months the angle of the sun becomes lower.UVB radiation is weaker and less available, particularly in latitudes above 35N (which includes most of North India).People also stay indoors more and cover up due to cold weather.This results is that skin produces far less Vitamin D