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All because the main component semaglutide reacts negatively to high temperatures, so it may impact the way it works

For example, if you started a GLP-1 in September 2024 with a BMI of 37 but in July 2026 youve lost weight and now have a BMI of 34, the prescriber should attest in the prior authorization request that you met the BMI criteria of 35 or over when the GLP-1 therapy started

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Understanding how to maximize the value of each vial reduces waste and keeps your protocol sustainable long-term

NICE guidance recommends fertility investigation if pregnancy has not occurred after 12 months of regular unprotected intercourse, or after 6 months if the female partner is aged 36 or over