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It is found that 93% of genomic regions of mice are arranged in an order similar to that of human beings and they are characterized by inexpensive feeding, rapid reproduction, easy modeling and small inter-individual differences that facilitate the observation of parallel experiments

In the type 2 diabetes group, the sample size was 710 patients

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Adults with a body mass index of at least 27 kg/m2 and glycated hemoglobin levels between 7 and 10% who had been diagnosed with type 2 diabetes for at least 180 days prior to screening were included in the double-blind, double-dummy study

Mice commonly used in current experimental studies include C57BL/6J mice, Kunming mice and gene-deficient mice (Table II)