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Patients were monitored for a maximum of 24 months from treatment initiation until the initial diagnosis of a neuropsychiatric outcome, death, loss to follow-up, or end of study

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For PCOS specifically, injections carry practical advantages: once-weekly dosing reduces medication adherence barriers, the appetite-suppressing effect is more pronounced and immediate, and cost-effectiveness matters when treatment may extend 12-18 months to fully restore cycle health