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Which makes sense with the, with the VEGF pathway

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This creates a devastating feedback loop: the lack of glutathione allows oxidative stress to run rampant, which further impairs the methylation cycle, which in turn prevents the production of more glutathione

It affects appetite, fullness, digestion, and metabolic signaling

Early research done on cells in a lab shows that berberine may reduce visceral fat, the type of fat stored deep in the abdomen that surrounds organs and is linked to obesity and adverse health outcomes