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"In any case, we believe that the observed effect reflects the mechanism of action inherent in targeting the GLP-1 receptor." Braca said they decided to investigate the potential impact of GLP-1 on migraine based on previous work by their research team, which suspected that impaired intracranial pressure control plays a role in the pathophysiology of migraine

doi: 10.1016/s0090-4295(99)00129-6 121 PlatzEAPollakMNRimmEBMajeedNTaoYWillettWCet al

Due to the continual rise in the number of people living with obesity, there is an increased demand for easily accessible medications that provide significant long-term weight loss while still fitting into patients' daily routines

Fisher M, VandenBranden M, Findlay K, Burchell B, Thummel K, Hall S, Wrighton SA: Tissue distribution and interindividual variation in human UDP-glucuronosyltransferase activity: relationship between UGT1A1 promoter genotype and variability in a liver bank